{"id":14361,"date":"2026-04-09T06:41:11","date_gmt":"2026-04-09T06:41:11","guid":{"rendered":"https:\/\/alfatherm.com\/hvac-sustavi-bolnice-clean-room\/"},"modified":"2026-04-15T13:15:22","modified_gmt":"2026-04-15T13:15:22","slug":"hvac-system-hospitals-clean-room","status":"publish","type":"post","link":"https:\/\/alfatherm.com\/en\/hvac-system-hospitals-clean-room\/","title":{"rendered":"HVAC systems in hospitals and clean room technologies; design, standards and performance"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"14361\" class=\"elementor elementor-14361 elementor-14347\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f0fb730 e-con-full e-flex e-con e-parent\" data-id=\"f0fb730\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-80eb989 elementor-widget elementor-widget-text-editor\" data-id=\"80eb989\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>HVAC systems in hospitals and clean room systems are essential for ensuring safe and sterile conditions in modern healthcare infrastructure.<\/p><blockquote><p>The design and construction of HVAC systems in hospitals are the most demanding engineering tasks in the field of mechanical installations. In these facilities, HVAC is not just a support for the building, but an integral element of the medical process. The requirement for precise control of the microclimate, cleanliness and direction of air flow arises from the need to prevent the spread of pathogens, ensure sterility in critical areas and enable the safe operation of medical equipment and personnel, and ultimately provide healthy and safe treatment of patients.<\/p><\/blockquote><p>Hospitals have one of the largest shares of technical systems in relation to the gross floor area of the facility, and these systems have complex interdependencies that must be included at the earliest stages of design.<\/p><p>Therefore, it is important that HVAC systems are included in the architectural and functional planning of the hospital at an early stage. The location of the engine rooms, the guidance of installation routes through the technical floors, the alignment with the structure, medical gases and electrical installations require a methodological approach and precise coordination.<\/p><p>Today, BIM technologies such as Revit, Navisworks, and platforms such as ACC are the standard because they enable digital collision resolution and maintenance optimization before the start of physical performance.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5419384 e-flex e-con-boxed e-con e-parent\" data-id=\"5419384\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-537f5ff elementor-widget elementor-widget-text-editor\" data-id=\"537f5ff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><span style=\"color: #003366;\"><strong>Specifics of microclimate and hygiene requirements<\/strong><\/span><\/h3><p>In contrast to standard facilities, microclimatic requirements in hospitals are defined according to the clinical function of the space. There are no universal settings.<\/p><p>Operating rooms, intensive care units, sterile preparations, transplant blocks, laboratories, patient rooms and biological waste treatment areas require different temperature, humidity and aerobiological parameters.<\/p><p>It is precisely because of this heterogeneity that the designer does not dimension the system for a &#8220;facility&#8221;, but for a series of separate process zones that must act as one functional system without mutual contamination risk.<\/p><h5><span style=\"color: #003366;\"><strong>Key requirements include:<\/strong><\/span><\/h5><p><span style=\"color: #003366;\"><strong>Air quality (IAQ) and high-efficiency filtration<\/strong><\/span><\/p><p>Air quality in a hospital is not a subject of the category of comfort, but an element of health safety. Higher stage filtration, including HEPA standards, is used in high-risk areas where reduced particle count, controlled turbulent or laminar flow, and strictly defined air exchanges are required.<\/p><p>The increased number of changes is not only a technical parameter, it allows for faster removal of biologically or chemically contaminated air volumes and improves the sterility and stability of the micro environment.<\/p><p><span style=\"color: #003366;\"><strong>Control of pressures and air flows<\/strong><\/span><\/p><p>Pressure control and airflow management are one of the key mechanisms to prevent cross-contamination in hospital facilities.<\/p><p>The system is based on establishing a cascade of pressures between different rooms and functional zones in order to define the direction of air flow and prevent the mixing of clean and contaminated volumes.<\/p><p>Most often, a reference point is defined in the sterile or central zone, from which the relations of overpressure to the areas that need to be protected and negative pressure to areas with increased risk are set.<\/p><p>The pressure cascade is not universal \u2014 it is shaped according to medical procedures and processes carried out in space, and is determined by a process engineer, taking care about the complexity of the functions that take place inside the hospital.<\/p><p>The requirements vary significantly depending on the function of individual hospital units, for example:<\/p><ul><li><strong><em>Operating rooms and intensive care units<\/em><\/strong> \u2013 require the highest level of sterility control and precise maintenance of temperature, relative humidity and above pressure to prevent contaminated air from entering.<\/li><li><strong><em>Laboratories and waste treatment areas <\/em><\/strong>\u00a0\u2013 equipped with special ventilation systems and vacuum to prevent the spread of odors, pathogens and harmful substances to the rest of the facility.<\/li><li><strong><em>Sensitive departments\u00a0<\/em><\/strong> \u2013 use defined microclimate barriers (PALs and MALs) for maintenance stable conditions and the required level of cleanliness.<\/li><li><strong><em>Contaminated rooms\u00a0<\/em><\/strong> \u2013 separated into separate ventilation zones served by special air-conditioning chambers, thus ensuring fully controlled air movement.<\/li><\/ul><p><span style=\"color: #003366;\"><strong>Precise temperature and humidity control<\/strong><\/span><\/p><p>It is necessary to maintain specific and stable parameters in different rooms, which is essential for comfort, but also for the functioning of sensitive medical equipment and the storage of medicines.<\/p><blockquote><p>Stable parameters are achieved by high-quality air conditioning chambers, accurate and calibrated sensors, advanced automation (BMS) and control of thermal loads from equipment and personnel.<\/p><\/blockquote><p>A sufficient number of air exchanges and proper segmentation of critical zones further ensure that the microclimate remains within the prescribed tolerances.<\/p><p><span style=\"color: #003366;\"><strong>Heating and cooling systems <\/strong><\/span><\/p><p>Heating, cooling and ventilation (HVAC) systems are a key technical infrastructure of modern hospitals, as they create strictly controlled conditions without which health processes cannot function. Their role is to ensure appropriate microclimatic conditions: temperature, relative humidity and air quality, in different hospital rooms, depending on their purpose.<\/p><p>Cooling systems include refrigeration devices such as chillers and split systems. They enable the maintenance of comfortable temperatures during the summer months, but also ensure the cooling of medical equipment and server systems that produce significant amounts of waste heat during operation.<\/p><p>\u00a0Steam production and distribution systems are important for generating steam that is used to humidify the air in air handling units, thereby maintaining the required humidity values in the room.<\/p><p>Key things that are important for these systems:<\/p><ul><li><span style=\"color: #003366;\"><strong>Reliability and safety<\/strong><\/span><\/li><\/ul><p>HVAC systems in hospitals must be extremely reliable and designed with the appropriate level of redundancy.<\/p><p>This includes ensuring redundancy in the selection of fans, backup power supplies, and other safety mechanisms that ensure continuous operation even in the event of a failure or power outage.<\/p><p>Such solutions are especially important in critical rooms, such as operating rooms and high-cleanliness zones, where interruption of ventilation can put at risk patient safety and health requirements.<\/p><ul><li><strong><span style=\"color: #003366;\">Ventilation as the key to preventing cross-contamination <\/span><\/strong><\/li><\/ul><p>In a hospital environment, ventilation, in addition to the supply of fresh air, plays a crucial role in preventing the transmission of microorganisms through the air. A properly designed ventilation system must ensure:<\/p><ul><li>Directional airflow<\/li><li>Efficient (two-stage or three-stage) filtration with high-efficiency filters<\/li><li>Continuous air exchange in accordance with standards (e.g. 12\u201320 air exchanges in operating room, about 10 changes in PAL\/MAL zones, and 4\u20136 changes in meeting rooms and patient rooms).<\/li><\/ul><p><strong>An interesting fact <\/strong>is that operating rooms use HEPA H14 filters (the highest clinical category). Such a filter can stop particles smaller than the SARS-CoV-2 virus.<\/p><h3><span style=\"color: #003366;\"><strong>Domestic hot water and Legionella control<\/strong><\/span><\/h3><p>Domestic hot water preparation in hospitals is one of the most sensitive technical areas, with extremely strict hygiene requirements. Legionella spp. remains the greatest risk to hot water systems, and the intensity of the infections it causes imposes a clearly defined approach to design, monitoring and maintenance.<\/p><p>\u00a0The reason for this is that this bacterium causes Legionnaires&#8217; disease \u2013 a terrible and potentially fatal infection of the respiratory system, which is transmitted by inhaling contaminated aerosol. That is why the prevention of its development must be a priority in every hot water system.<\/p><p>The specificity of hospitals is further emphasized by the high consumption of water and the vulnerability of the user population, which requires systems that can ensure stable temperatures, avoiding stagnation, constant circulation and disinfection.<\/p><p>In practice, centralized systems with heat exchangers and accumulators are most often used, which enable the safe distribution of DHW (domestic hot water) with the monitoring of critical points.<\/p><p>\u00a0Alternatively, systems with flow-through preparation reduce the risk of stagnation, but require more powerful inverters and more stable load control.<\/p><p>The integration of renewable energy sources is becoming more and more common, especially in the preheating segment, where energy savings are achieved without compromising hygiene standards.<\/p><h3><span style=\"color: #003366;\"><strong>Central Monitoring and Control System\u00a0<\/strong><\/span><\/h3><p>The central monitoring and control system plays a key operational role in the operation of hospital HVAC installations as it integrates the monitoring of microclimate, pressures, air flow, humidification, energy consumption and safety parameters into a single control platform.<\/p><p>This allows for precise maintenance of conditions in areas with special operating regimes, including operating halls, isolation units, intensive care units and laboratories, where deviations from setpoints directly affect the medical process.<\/p><p>The system continuously monitors the operation of fans, pumps, air conditioning chambers, heat exchangers and air quality sensors, and alarms and reacts to deviations in a timely manner.<\/p><p>Such an approach reduces the risk of contamination incidents, optimizes energy consumption, and enables quick intervention without interrupting the operation of the facility.<\/p><blockquote><p>The integration of CNUS\/BMS into design and construction is therefore not only a question of automation, but also a tool that achieves stability, safety and energy efficiency of hospital infrastructure.<\/p><\/blockquote><h3><span style=\"color: #003366;\"><strong>Standards &amp; Regulation<\/strong><\/span><\/h3><p>HVAC systems in hospitals are designed and built in accordance with international and national regulations, whereby the following are applied in practice:<\/p><ul><li><strong>ASHRAE 170 \u2013 Ventilation of Health Care Facilities<\/strong><\/li><li><strong>Applicable national standards<\/strong><\/li><li><strong>National laws and regulations on construction and technical systems<\/strong><\/li><\/ul><p>These standards define key parameters such as required air exchanges, filtration levels, pressure regimes, microclimatic conditions, and safety requirements.<\/p><h3><span style=\"color: #003366;\"><strong>Installation in hospitals<\/strong><\/span><\/h3><p>Performing HVAC installations in hospitals requires precise monitoring of project requirements and constant coordination with all technical disciplines, including construction, electrical engineering, medical gases and automation.<\/p><p>The requirements for creating and monitoring dynamic plans are also significantly higher than in standard projects, because a large number of specialized professions are present on the construction site at the same time, which have to work in fully coordinated phases.<\/p><p>During the installation of the duct network, it is necessary to ensure the protection of all elements in order to prevent contamination with dust and impurities, which can later affect the air quality and the operation of the system.<\/p><p>A special focus is placed on <strong>commissioning<\/strong>, in which the functionality of the system is checked by balancing the flow of air and water, checking the automation, the response of alarm functions and the stability of pressures in special zones. After that, measurements and validation are carried out, including checking differential pressures, air purity, comfort conditions and operation in different facility regimes.<\/p><p>Long-term reliable hospital infrastructure can only be achieved through precise execution, a disciplined commissioning process and documented proof that the system in operation meets the designed technical and hygienic requirements.<\/p><blockquote><p>Designing and implementing HVAC systems in hospitals is not just a technical task \u2013 it is a responsibility towards the health of patients and the safety of doctors. Expertise, hygiene requirements, energy efficiency and innovative solutions need to be combined to keep systems running reliably and safely.<\/p><\/blockquote><h3><span style=\"color: #003366;\"><strong>Cooperation with Alfa Therm<\/strong><\/span><\/h3><p>Alfa Therm is continuously present on the European market and is recognized as a reliable partner in the design and implementation of specific HVAC and clean room systems for renowned pharmaceutical companies. Projects are implemented in accordance with applicable international standards and regulatory requirements (GMP, ISO), which ensures a high level of quality and safety.<\/p><p>Such projects represent a significant challenge to which our engineers successfully respond. We participate in the conception, design, BIM coordination, execution, supervision and commissioning process &#8211; from idea to functionality.<\/p><p>Today, we are able to transfer the acquired specific knowledge and expertise to the domestic market. We choose these leading projects:<\/p><ul><li><a href=\"https:\/\/alfatherm.com\/skbc-mostar\/\">University Clinical Hospital in Mostar<\/a>, including the recently built hospital Clinic for Children&#8217;s Diseases<\/li><li>Special hospital <a href=\"https:\/\/www.svkatarina.hr\/\">St. Catherine in Zagreb<\/a><\/li><li>Hospital<a href=\"https:\/\/www.bolnicabijeljina.com\/\"> Sveti Vra\u010devi in Bijeljina<\/a><\/li><li>Newly opened <a href=\"http:\/\/alfatherm.com\/bolnica-trebinje\/\">hospital in Trebinje.<\/a><\/li><\/ul><p>Our experience covers the entire process; from the design of HVAC systems for hospitals to the implementation and validation of clean room spaces.<\/p><p>We are ready to apply our experience and standards to your next project.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>HVAC systems in hospitals represent a critical infrastructure for maintaining sterile and safe conditions. Precise control of the microclimate, air filtration, and pressure regulation are essential for preventing contamination and ensuring the optimal functioning of medical processes.<\/p>\n","protected":false},"author":3,"featured_media":14363,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","footnotes":""},"categories":[66],"tags":[207,173,208,209,210,211,220,212,217,103,213,214,219,218,215],"class_list":["post-14361","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-ashrae170","tag-bms","tag-bms-2","tag-bolnice","tag-bolnickaventilacija","tag-cleanroom","tag-heatingandcooling","tag-hepa","tag-hospitalsventilation","tag-hvac-en","tag-kgh","tag-legionela","tag-legionella","tag-microclimateinhospitals","tag-mikroklimaumolnicama"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>HVAC systems in hospitals and clean room technologies; design, standards and performance - Alfa Therm<\/title>\n<meta name=\"description\" content=\"Design and implementation of HVAC systems in hospitals and clean room areas according to GMP and ISO standards. 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